Herbal drugs have been widely used throughout the course of history. Traditional\nknowledge based on religious beliefs and/or experience has been transmitted orally between\ngenerations. First attempts to provide scientific evidence came in the 19th century when potent\ncompounds were first isolated. Since then, modern pharmacology theory has been assumed by\nphytotherapy. Scientists have tried to elucidate the molecular mechanism of each compound and,\nfor a pharmacological indication, propose an effective and secure dose. Stepwise, clinical trials\nconfirm the benefits of herbal drug use in therapeutics, especially for chronic diseases. However,\nherbal drugs exert pleiotropic effects, and there is still a need for a complete, rational, and widely\naccepted theory that can explain phytotherapy efficacy. The ââ?¬Å?-omicsââ?¬Â might help with this matter.\nStudies of modification in the gene expression profile, the metabolome, and the physiopathological\nstate after the administration of a herbal extract could provide relevant information that verifies\nherbal therapies
Loading....